It is a story that relates to the corruption of the American Dream.

Entwined in the provocative reputation of America is the celebrated ideal of the American Dream, a fantasy of independence combined with the opportunity to attain wealth through hard work. At the heart of the American Dream lies the aspiration of eternal bliss, which is always 'just around the corner.' The American Dream does not allow complacency; the need for continual progress is always present, urging one to work a little harder....

Jay Gatsby never does fulfill the American Dream.

Chris McCandless lived his American dream by walking alone into the wilderness of Alaska.
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They seem to have fulfilled the American Dream.

The characters in the novel are divided into two groups: the rich upper class and the poorer lower class(West egg and East egg) though the main characters only try to make their lives better, the American dream they are all trying to achieve is eventually ruined by the harsh reality or life.

It seems that the American Dream really can consume a person.

Mr. Sanchez was also a charitable man with a heart for helping children, in particular. As an ambassador, he and his late wife, Juanita, helped get a number of orphans in Honduras placed with American families – including their own with the adoption of daughter Kristina. They later founded an orphanage in Mexico and funded it for 25 years.

But Gatsby isn't the only example of trying to fulfill the American dream in this book.
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‘Walt Disney’ and the American dream on PBS - SFGate

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Whatever happened to the American Dream we knew eighty years ago